Central nervous system 병변의 재발 없이 mental nerve를 침범한 precursor T-cell leukemia/lymphoma의 증례 보고
A Case Report of Precursor T-cell Leukemia/lymphoma Accompanying Mental Nerve Invasion without Recurrence for Central Nervous System
한선희, 남정우, 박혁, 김형준, 김남희, 김현실, 육종인,
소속 상세정보
한선희 ( Han Seon-Hui ) - 연세대학교 치과대학 구강병리학교실
남정우 ( Nam Jung-woo ) - 연세대학교 치과대학 구강악안면외과학교실
박혁 ( Park Hyok ) - 연세대학교 치과대학 구강악안면외과학교실
김형준 ( Kim Hyung-Jun ) - 연세대학교 치과대학 구강악안면외과학교실
김남희 ( Kim Nam-Hee ) - 연세대학교 치과대학 구강병리학교실
김현실 ( Kim Hyun-Sil ) - 연세대학교 치과대학 구강병리학교실
육종인 ( Yook Jong-In ) - 연세대학교 치과대학 구강병리학교실
KMID : 0829220100340050299
Abstract
Facial numbness restricted to the distribution of the mental nerve(mental neuropathy) is called "numb chin syndrome". The clinical importance of this syndrome is associated with first recognition of involvement of malignant diseases. The malignant neoplasm with numb chin syndrome show rapid progression and high mortality. We present a 43-year-old female who had been treated by radiotherapy for precursor T-cell leukemia/lymphoma involving the central nervous system(CNS) previously and later developed mental nerve invasion without central nervous system recurrence. MRI images revealed the CNS tumor mass remitted, and there was no identified peripheral nervous system(PNS) involvement including the mental nerve invasion, nevertheless the patient complained of consistent numbness and pain on right mandibular area. This is the first case of precursor T-cell leukemia/lymphoma accompanying mental nerve invasion without recurrence for central nervous system. Proper interpretation for mental neuropathy may lead to the prompt diagnosis and therapeutic intervention.
키워드
Precursor T-cell leukemia/lymphoma; Central nervous system (CNS); Invasion; Mental neuropathy; Numb chin syndrome
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